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Most (81.4)) of the CGRP /SPergic boutons were galanin and approximately half (49.0)) of these cost of mmb-chminaca wyoming contained CART. Almost all (97.9)) randomly selected calcitonin generelated peptide (CGRP ))immunoreactive terminals were substance P (SP))positive and CART was detected in approximately half (48.6)) of them.

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The innervation density from these boutons did not differ significantly between either the different neurochemical or the morphological subclasses of these cells. This suggests a nonselective innervation of lamina I projection neurons from a subpopulation of CGRP /SP afferents containing CART peptide. These results provide anatomical evidence for involvement of CART peptide in spinal pain transmission. Citing Literature.

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Nonselective innervation of lamina I projection neurons by cocaine and amphetamineregulated transcript peptide (CART )immunoreactive fibres in the rat spinal dorsal horn Dr Z. Puskr, as above. Email: Abstract Cocaine and amphetamineregulated transcript (CART ) peptides have been implicated in spinal pain transmission. A dense.

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